A web database of the Italian genetic variability


Believing in the utility of large population-specific databases, especially for a complex population like the Italian one, the Network for Italian Genomes (NIG) provides variant frequencies as a free tool for both clinicians and researchers.

Three datasets are currently available (4212 exomes):

  • 1492 Italian clinical cases and trios affected by different diseases;
  • 1686 Italian healthy controls, with well-characterized ancestry in the four Italian macro-areas (North, Center, South and Sardinia);
  • 1034 Italian SARS-CoV-2 PCR positive individuals (1013 unrelated), from very severe (intubated) to asymptomatic cases.

Network for Italian Genomes

NIG


  • 1492 Italian individuals (1098 unrelated)
  • Cases with different diseases
  • Whole-Exome Sequencing
  • Includes trios

NIG - Exomes from ITaly

NIG-ExIT


  • 1686 unrelated Italian individuals
  • Healthy controls
  • Whole-Exome Sequencing
  • Well-characterized ancestry

NIG-COVID-19 exomes

GEN-COVID